Do Herbal Supplements for Men Actually Work? The Evidence (2026)

Do Herbal Supplements for Men Actually Work? The Evidence (2026) — Blue Power

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In 30 seconds

Evidence: The only ingredient with an authorised claim is zinc: Zinc contributes to the maintenance of normal testosterone levels in the blood. The rest is trial evidence, not product claims.

Timing: Most of the trials cited above measured outcomes at 8–12 weeks, so any fair test of a herbal ingredient needs that long, not days.

Next step: See Blue Power's fully disclosed 7-ingredient formula, with each ingredient's dose and evidence grade listed on the product page.

“Do herbal supplements for men actually work?” is a fair question and a frustrating one to answer briefly — because the honest answer is “some do, in specific situations, with specific evidence; some do not.” The category averages out to mediocre because most products are sold without standardisation, at sub-clinical doses, with marketing that overstates what the trials support. The few ingredients that are genuinely evidence-backed look very different on closer inspection from the ones that ride that label without earning it.

This UK evidence review walks through seven of the most commonly sold herbal ingredients in men’s health products, grades them against the same standard (regulatory approval and human RCT data), and identifies which ones deliver real benefit, which ones come close, and which ones do not. The aim is the opposite of an “everything works” product page: just the data, with the funding sources, sample sizes, and limitations on the table. For deeper dives on individual ingredients, see the linked Shilajit, Tongkat Ali, and Korean Ginseng guides.

TL;DR — Do Herbal Supplements for Men Work? Quick Verdict
  • Strong evidence: Zinc — only ingredient with an EFSA-approved testosterone claim (EFSA Claim 301)
  • Moderate evidence: Tongkat Ali (5-RCT meta-analysis SMD 1.352, p=0.001), Korean Ginseng (Cochrane review, 9 RCTs / 587 men), Shilajit (one strong RCT, manufacturer-funded), Maca (desire effect without testosterone change), L-Arginine (mild ED, high doses)
  • Weak evidence: Horny Goat Weed — in vitro PDE5 effect, no published human RCTs of consequence
  • None of these ingredients matches the effect size of sildenafil for erectile function (57% vs 21% successful intercourse, JAMA, 2002)
  • What works in herbals: upstream factors — testosterone, cortisol, blood-flow precursors — over weeks to months
  • What does not work: marketing claims of multi-fold testosterone increases at non-clinical doses, proprietary blends, products without standardisation

How We Rated the Evidence

Three grades, applied consistently across all seven ingredients:

  • Strong evidence: regulatory-approved health claim (EFSA), or multiple high-quality RCTs replicated by independent groups, or a Cochrane review with at least moderate certainty.
  • Moderate evidence: at least one rigorous placebo-controlled RCT plus supportive secondary data (meta-analysis with caveats, secondary trials), with the limitation that sample sizes are small or studies are manufacturer-funded.
  • Weak / insufficient evidence: only animal data, in vitro mechanism without human RCTs, or human studies with serious methodological problems.
The evidence-funding distinction: A manufacturer-funded RCT is not invalidated by its funding, but the result should be considered preliminary until an independent group replicates it. EFSA-approved health claims are the strongest backing — they require systematic review of all available evidence and are not granted lightly. Of the ingredients in this guide, only zinc holds an EFSA testosterone claim.

1. Zinc — The Only Ingredient with a Regulatory-Approved Testosterone Claim Strong Evidence

Researcher reviewing ingredient evidence on a tablet — representing the EFSA evidence assessment process
Of seven popular herbal supplement ingredients, only zinc has secured an EFSA-approved testosterone health claim.

Zinc is unique on this list. It holds an EFSA-approved health claim (ID 301): “Zinc contributes to the maintenance of normal testosterone levels in the blood.” It also has approved claims for fertility and reproduction (ID 297/300) and for normal immune function. No other ingredient sold for men’s testosterone in the UK can legally make this claim (EFSA Journal, 2010).

The clinical evidence behind that approval: in a study of 9 zinc-deficient elderly men (mean age 64), six months of supplementation nearly doubled serum testosterone from 8.3 to 16.0 nmol/L (p=0.02) (Prasad et al., Nutrition, 1996). The effect is concentrated in men with deficiency or marginal status — in zinc-sufficient men, supplementation does not push levels higher. The benefit, in other words, is preventing deficiency-driven decline rather than enhancing already-healthy levels.

EFSA Claim ID 301: “Zinc contributes to the maintenance of normal testosterone levels in the blood.” This is the only EFSA-approved testosterone-related health claim for any ingredient sold in men’s supplements in the UK or EU. The 100% NRV (Nutrient Reference Value) is 10mg/day — the dose at which the claim applies (EFSA Journal, 2010).

2. Tongkat Ali — Promising Testosterone Data, Growing Evidence Base Moderate Evidence

Tongkat Ali (Eurycoma longifolia) has the strongest emerging testosterone data after zinc. A 2022 meta-analysis of 5 RCTs covering 232 participants found a statistically significant increase in total testosterone (SMD 1.352, 95% CI 0.565–2.138, p=0.001), with the effect strongest in hypogonadal men (SMD 1.861, p=0.002) (Leisegang et al., Medicina, 2022). A 6-month double-blind RCT in men with age-related androgen decline found 200mg/day alongside exercise improved both erectile function and total testosterone versus placebo (Leitão et al., 2021).

The honest limitation: the meta-analysis covers 232 participants, modest by pharmaceutical standards. The pooled studies were largely manufacturer-funded (Biotropics Malaysia’s Physta extract), although the meta-analysis itself is academically independent. The convergence of industry and independent results is what earns the moderate-evidence rating.

3. Korean Ginseng — The Largest Evidence Base for Erectile Function Moderate Evidence

Korean Ginseng has been studied more than any other herb on this list for men’s sexual health. A 2021 Cochrane-style review of 9 RCTs (587 men) found the ability to achieve intercourse improved 2.55× vs placebo (RR 2.55, 95% CI 1.76–3.69), with moderate-certainty evidence (Lee et al., 2021). A larger 2025 meta-analysis of 14 RCTs (1,227 men) found significant improvements in erectile function (SMD 0.41), sexual desire (SMD 0.45), and even serum testosterone (SMD 0.23) (Ho et al., 2025).

4. Shilajit — Striking Results, but Independence Questions Moderate Evidence

Shilajit’s headline RCT is a 90-day, double-blind, placebo-controlled trial in 75 men aged 45–55: 250mg purified shilajit twice daily was associated with a 20.45% rise in total testosterone and 19.14% in free testosterone versus placebo (Pandit et al., Andrologia, 2016). The trial was funded by Natreon, the manufacturer of PrimaVie shilajit. The same group’s earlier open-label trial in oligospermic men showed a 23.5% testosterone increase (Biswas 2010). To date, no independent group has replicated the testosterone findings. The 2024 systematic review of 15 clinical studies (1,254 participants) found no serious adverse events — safety is solid; replication of the testosterone result is the open question.

5. Maca Root — Desire Without Testosterone Change Moderate Evidence

Maca (Lepidium meyenii) is unusual: a double-blind RCT found that 1,500mg and 3,000mg daily improved sexual desire from week 8, but without any change in serum testosterone or oestradiol (Gonzales et al., 2002). The mechanism appears to be central-nervous-system mediated. A 2010 systematic review of 4 RCTs concluded “limited evidence” (Shin 2010). A 2023 meta-analysis found a modest positive effect on erectile function in men with mild ED (MD 1.13, p=0.01).

6. L-Arginine — The Blood Flow Precursor Moderate Evidence

L-Arginine is the direct precursor to nitric oxide, the molecule that triggers blood vessel relaxation. The mechanism is uncontested; the question is whether the dose used in supplements matches the dose used in the trials. A multicentre double-blind RCT found 6g/day for 3 months significantly improved erectile function scores, with 74% of men showing improvement (Menafra et al., 2022). An earlier RCT using 5g/day found 31% improvement on L-arginine vs 12% on placebo (Chen 1999). For details on the wider blood-flow pathway, see our nitric oxide supplements guide for men.

7. Horny Goat Weed — The Ingredient That Does Not Have Human Evidence Weak Evidence

Horny goat weed (Epimedium) is one of the most commonly added ingredients to men’s health supplements and one of the least supported by human data. Its lead compound, icariin, is a mild PDE5 inhibitor in vitro — but its activity is roughly 1/80 of sildenafil, and there are no published human RCTs of erectile function with rigorous design. The handful of small clinical studies have used proprietary blends, not standardised icariin extract. As a single ingredient, the human evidence base does not support a confident effect claim.

Total Participants in RCTs / Meta-Analyses by Ingredient Total Participants in RCTs / Meta-Analyses by Ingredient Larger sample sizes = stronger evidence base; manufacturer-funded studies flagged in funding table below Korean Ginseng Tongkat Ali L-Arginine Maca Root Shilajit Zinc (deficient men) Horny Goat Weed 14 RCTs / 1,227 men (2025 meta-analysis) 5 RCTs / 232 men ~98 men (largest RCT) ~79 men (4-RCT review) 75 men (1 RCT, manufacturer-funded) 9 men (deficient subset, EFSA-backed claim) No rigorous human RCT
Sample size is not the only metric, but it is the easiest comparison. Korean ginseng has the largest body of human evidence for sexual health; horny goat weed has the smallest. Zinc’s small sample size is offset by EFSA regulatory backing.

Funding & Independence: A Quick Audit

A short transparency table for the headline studies:

Ingredient Lead Study Funding Independence
Zinc EFSA Claim 301 / Prasad 1996 EU regulatory + academic Independent
Tongkat Ali Leisegang 2022 meta-analysis Academic; pooled studies often industry-funded Mixed (meta independent)
Korean Ginseng Lee 2021 Cochrane review Cochrane Library Independent
Shilajit Pandit 2016 Natreon (PrimaVie manufacturer) Industry — awaiting independent replication
Maca Root Gonzales 2002 Academic (Peruvian university) Independent
L-Arginine Menafra 2022 Academic, multicentre Independent
Horny Goat Weed In vitro PDE5 mechanism Lab work, no rigorous human RCT Insufficient data

Editorial note — what this list actually says about the category: Out of seven popular herbal ingredients, one has regulatory approval (zinc), four have meaningful human RCT support but with caveats (Tongkat Ali, Korean Ginseng, Shilajit, L-Arginine), one has unusual evidence for desire without a hormone change (maca), and one is essentially marketing (horny goat weed as a single ingredient). The category averages out to underwhelming because most products are sold without standardisation, at sub-clinical doses. The few products that combine the right ingredients at the right doses with a proper Certificate of Analysis are a different proposition altogether — and the difference is precisely what determines whether “do herbal supplements work?” gets a yes or a no.

— Blue Power Research Team, reviewing the cited EFSA, Cochrane, and PubMed-indexed literature

How Herbal Supplements Compare to Prescription ED Treatments

The most honest comparison in this whole space is between the herbal evidence base and the sildenafil evidence base. Sildenafil’s 27-RCT meta-analysis (n=6,659) found 57% successful intercourse on sildenafil vs 21% on placebo — an effect size that no herbal ingredient on this list comes close to (JAMA Internal Medicine, 2002). For acute, on-demand erectile reliability, prescription PDE5 inhibitors are the evidence-led answer. For wider context on the herbal-vs-prescription decision, see our Horny Goat Weed review and the wider Tongkat Ali guide.

What the herbal literature points to is a different proposition: a daily upstream routine spanning hormonal, blood-flow and energy pathways, taken daily over weeks and months. That is not a sildenafil substitute — it is a different problem being solved. Many men over 40 use both, sequenced sensibly: a daily multi-ingredient formula for the foundation, and PDE5 inhibitors on demand when extra reliability matters.

Forms, Doses & Standardisation: What Separates Real Products from Marketing

Across all seven ingredients, four quality criteria separate evidence-aligned products from marketing-only products:

Quality criterion What to look for Why it matters
Standardisation % Eurycomanone for Tongkat Ali; ginsenosides for ginseng; fulvic acid for Shilajit The active compound count, not just the milligrams, is what the trials use
RCT-aligned dose Match the milligrams used in the published trial, not the brand’s suggested serving 50% of clinical dose ≈ 0% of clinical effect for many botanicals
Third-party Certificate of Analysis Identity, heavy metals, microbial, pharmaceutical adulterants The 2018 JAMA analysis of 776 tainted supplements is the structural risk
Dose transparency on the label Per-ingredient milligrams, not proprietary “blends” If the dose is hidden, comparison with the trial dose is impossible
The two-question test before buying a herbal supplement: 1) Does the label specify both the milligrams and the standardisation percentage of the active compound? 2) Can I compare those numbers to the dose used in the published trial? If the answer to either is no, what you are buying is not the product the trial measured. This single test eliminates a large fraction of the UK market.

Are Herbal Supplements Safe?

Across the seven ingredients in this guide, the safety picture at clinical doses is generally reassuring, but the risks worth flagging are real:

Who should consult a GP before starting a herbal stack:
  • Men on warfarin or other anticoagulants: Korean ginseng and high-dose omega-3 affect clotting
  • Men on diabetes medication: Korean ginseng and L-Arginine can compound glucose-lowering effects
  • Men on blood-pressure medication: L-Arginine and ginseng can affect BP
  • Men on PDE5 inhibitors: declare any blood-flow supplements to your pharmacist before purchase
  • Men with liver conditions: Tongkat Ali’s EFSA novel-food note and any unverified products warrant caution
  • Pregnant or breastfeeding women, under-18s: not studied for any of these ingredients

How to Choose Quality Herbal Supplements in the UK

Five practical filters that account for almost all of the difference between trial-grade and marketing-grade products:

  • Standardisation on the label. Eurycomanone %, ginsenoside %, fulvic acid %, icariin %. No percentage = no comparison to the trial.
  • Dose match to the published RCT. Tongkat Ali 200mg, Shilajit 500mg, Korean Ginseng 1,000–3,000mg root equivalent, L-Arginine 5–6g.
  • Third-party Certificate of Analysis. Heavy metals, microbial contamination, pharmaceutical adulterants.
  • UK or EU GMP certification. The floor, not the ceiling.
  • No proprietary blends. The per-ingredient mg should be on the label.

Why Does Blue Power Use the Evidence-Backed Ingredients?

Blue Power: The Evidence-Led Stack, Not the Long Marketing List

Blue Power was formulated to focus on the ingredients that actually clear the bar in this evidence review — not to pad the label. That is why the formula is short rather than long, and standardised rather than ratio-only:

  • Zinc 10mg (100% NRV) — Zinc contributes to the maintenance of normal testosterone levels in the blood.
  • Oat extract (Avena sativa) 10:1 50mg — a traditional oat botanical extract included at a named supporting dose
  • Shilajit 50mg — purified; see the evidence review above
  • Korean Ginseng 5:1 100mg — standardised; see the evidence review above
  • L-Arginine 50mg — nitric oxide precursor; see the evidence review above
  • Maca 50mg + Vitamin C 80mg — complementary pathways. Vitamin C contributes to the reduction of tiredness and fatigue.

Full formula: Oat extract (Avena sativa) 10:1 50mg · Shilajit 50mg · Maca Root 50mg · Korean Ginseng 5:1 100mg · L-Arginine 50mg · Zinc 10mg · Vitamin C 80mg · GMP certified, UK manufactured.

Try Blue Power — The Evidence-Led Daily Stack

Seven ingredients, one daily tablet, prioritised by evidence quality. UK manufactured, GMP certified, fully transparent dosing.

Get Blue Power — Free UK Delivery

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Reporting side effects. Food supplements are generally well tolerated, but if you notice an unexpected reaction to any supplement you can report it to the UK regulator through the MHRA Yellow Card Scheme. Always tell your GP or pharmacist about supplements you take, especially alongside prescription medicines.

Frequently Asked Questions About Herbal Supplements for Men

Do herbal supplements for men actually work?

Some do, in specific situations. Zinc has an EFSA-approved testosterone claim. Tongkat Ali has a meta-analysis of 5 RCTs (SMD 1.352, p=0.001). Korean Ginseng has a Cochrane-style review of 9 RCTs and a 2025 meta-analysis of 14 RCTs covering 1,227 men. Shilajit has one strong RCT, awaiting independent replication. Maca and L-Arginine have moderate evidence in specific contexts. Horny Goat Weed lacks robust human RCTs.

Are herbal supplements as effective as Viagra?

No. Sildenafil’s 27-RCT meta-analysis (n=6,659) found 57% successful intercourse on sildenafil vs 21% on placebo — an effect size no herbal ingredient on this list comes close to. Herbal supplements work upstream (testosterone, cortisol, blood-flow precursors, energy) over weeks to months. PDE5 inhibitors work downstream (vascular relaxation) on demand. They solve different problems.

Which herbal supplement has the strongest evidence for testosterone?

Zinc has the strongest regulatory backing (EFSA Claim 301), particularly in men with deficiency. Tongkat Ali has the strongest meta-analysis-level evidence (SMD 1.352, p=0.001 across 5 RCTs / 232 men), with the largest effect in hypogonadal men. Shilajit shows a striking ~20% increase in one RCT in men 45–55 but lacks independent replication.

How long do herbal supplements take to work?

Most published RCTs run 8–12 weeks at minimum. The Tongkat Ali studies show effects from 4 weeks but build through 12 weeks. The Shilajit testosterone trial used 90 days. The Korean Ginseng erectile-function trials run 4–8 weeks. Anyone promising acute effects from a daily herbal stack is overstating what the evidence supports — that is what PDE5 inhibitors do, not herbals.

Are herbal supplements regulated in the UK?

Yes, as food supplements. UK herbal supplements must comply with the Food Supplements Regulations 2003 and may not make health claims unless those claims are EFSA-approved (e.g., Zinc Claim 301 for testosterone). The MHRA can take action against products that make medicinal claims without authorisation. However, the regulatory framework is lighter than for medicines — which is why standardisation, third-party CoAs, and GMP certification matter so much.

Can I take herbal supplements with prescription medication?

Sometimes, but always check first. Korean ginseng can affect blood-thinners, blood-pressure medication, and diabetes drugs. L-Arginine can compound nitrate effects. Shilajit and Tongkat Ali should be reviewed by anyone with liver conditions. Always declare your supplement stack to your GP or pharmacist when starting any new prescription — it is the question doctors most often have to ask twice because patients forget to mention them.

The Bottom Line: Do Herbal Supplements Work for Men?

Of seven of the most-sold herbal ingredients in UK men’s health products, one has regulatory approval (zinc), four have meaningful human RCT data with caveats (Tongkat Ali, Korean Ginseng, Shilajit, L-Arginine), one has unusual evidence for desire without hormonal change (maca), and one essentially does not have rigorous human evidence as a single ingredient (horny goat weed). The honest answer to “do herbal supplements work?” depends entirely on which supplement, in which dose, with which standardisation, in which population.

The structural problem with the category is not that the good ingredients do not work — the meta-analyses, Cochrane reviews, and EFSA claims show several of them do, in the contexts they were studied. The problem is that most products on the shelf are not the products that were studied. Solving that is a quality problem, not a science problem — standardisation on the label, dose match to the trial, third-party CoA, no proprietary blends.

For UK men weighing the question for themselves, the most efficient approach is a short, transparent stack of the ingredients with the strongest evidence (zinc, Tongkat Ali, Shilajit, Korean Ginseng, L-Arginine), at clinical-style doses with verified standardisation, taken daily for at least 8–12 weeks before judging the effect. Skip the long marketing lists and the proprietary blends. The category gets better one product at a time when the buyer asks for the things that actually separate trial-grade from marketing-grade.

Food supplement information. Blue Power is a food supplement, not a medicine. It is not intended to diagnose, treat, cure or prevent any disease. Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Do not exceed 1 tablet per day. Not suitable for under-18s or pregnant/breastfeeding women. Consult a healthcare professional before use if you are taking medication or have a medical condition. See our editorial policy and fact-checking process.
References & Sources (expand)
  1. EFSA (2010). Scientific opinion on the substantiation of health claims related to zinc. EFSA Journal 8(10):1819 (Claim ID 301). EFSA Journal
  2. Prasad AS et al. (1996). Zinc status and serum testosterone levels of healthy adults. Nutrition 12(5):344–8. PubMed 8875519
  3. Leisegang K et al. (2022). Eurycoma longifolia improves serum total testosterone in men: meta-analysis of 5 RCTs. Medicina 58(8):1047. PMC9415500
  4. Leitão AE et al. (2021). 6-month RCT of Eurycoma longifolia + concurrent training. Maturitas. PubMed 33541567
  5. Lee HW et al. (2021). Ginseng for erectile dysfunction: Cochrane systematic review. Cochrane Database. PMC8987140
  6. Ho JCK et al. (2025). Panax ginseng for male sexual function: meta-analysis of 14 RCTs / 1,227 men. J Tradit Complement Med. PMC12902307
  7. Hong B et al. (2002). Korean Red Ginseng for erectile dysfunction: double-blind crossover RCT. J Urology. PubMed 12394711
  8. Pandit S et al. (2016). Clinical evaluation of purified Shilajit on testosterone levels. Andrologia. PubMed 26395129
  9. Gonzales GF et al. (2002). Effect of Lepidium meyenii (maca) on sexual desire and serum testosterone. Andrologia. PubMed 12472620
  10. Shin BC et al. (2010). Maca for sexual function: systematic review of 4 RCTs. BMC Complement Altern Med. PubMed 20691074
  11. Menafra D et al. (2022). L-arginine in male erectile dysfunction: multicentre double-blind RCT. J Endocrinol Invest. PubMed 34973154
  12. Fink HA et al. (2002). Sildenafil for male erectile dysfunction: meta-analysis. JAMA Internal Medicine. jamanetwork.com
  13. Tucker J et al. (2018). Unapproved pharmaceutical ingredients in dietary supplements with US FDA warnings. JAMA Network Open. PMC6324457

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